HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Amino-2,3-difluorophenol → N-(2-Hydroxy-3,4-difluorophenyl)-2-fluoro-5-nitrobenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Amino-2,3-difluorophenol | HCID 2778441 | — |
| Reactant | 2-Fluoro-5-nitrobenzoyl chloride | HCID 10976570 | — |
| Product | N-(2-Hydroxy-3,4-difluorophenyl)-2-fluoro-5-nitrobenzamide | HCID 21884418 | — |
Reaction Steps
Prepared by the method of Example 15a), from 2-amino-5,6-difluorophenol (334 mg, 2.3 mmol) and 2-fluoro-5-nitrobenzoyl chloride (468 mg, 2.3 mmol) the subtitle compound was obtained. The product was used directly in the next step without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07138425B2 |
| Source dataset | uspto-grants-2006_11 |
| ORD ID | ord-12e6546ed09946f798cbd255c15c496d |
| Source note | uspto-grants-2006_11 |