Lithium Hydroxide → HCID 21884331, compound

HRID 722615Notes

Reaction equation

C[O:2][C:3]([C:5]1[C:13]2[O:12][C:11]([C:14]3[CH:19]=[CH:18][CH:17]=[C:16]([N+:20]([O-:22])=[O:21])[CH:15]=3)=[N:10][C:9]=2[CH:8]=[CH:7][CH:6]=1)=[O:4].[OH-].[Li+]>>[N+:20]([C:16]1[CH:15]=[C:14]([C:11]2[O:12][C:13]3[C:5]([C:3]([OH:4])=[O:2])=[CH:6][CH:7]=[CH:8][C:9]=3[N:10]=2)[CH:19]=[CH:18][CH:17]=1)([O-:22])=[O:21]

Participants

Reactant 2

HCID 3939Lithium Hydroxide

HCID 69585056HCID 69585056, compound

Product 1

HCID 21884331HCID 21884331, compound

Procedure

Prepared by the method of Example 76c), from 2-(3-nitrophenyl)benzoxazole-7-carboxylic acid methyl ester (600 mg, 2.01 mmol) and lithium hydroxide (240 mg, 10.06 mmol) the subtitle compound was obtained, (442 mg, 77%). The product was used directly in next step without purification.

Sources & evidence

ORD record: ord-71b61d8caf66426cb38ca7049f4d9b1f
Source dataset: uspto-grants-2006_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07138425B2

Reaction notes

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