HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(3-Nitro-4-methoxyphenyl)-5-(2-benzothiophenyl)benzoxazole → 2-(3-Amino-4-methoxyphenyl)-5-(2-benzothiophenyl)benzoxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(3-Nitro-4-methoxyphenyl)-5-(2-benzothiophenyl)benzoxazole | HCID 21884548 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 2-(3-Amino-4-methoxyphenyl)-5-(2-benzothiophenyl)benzoxazole | HCID 21884573 | — |
Reaction Steps
Prepared by the method of Example 15e), from 2-(3-nitro-4-methoxyphenyl)-5-(2-benzothiophenyl)benzoxazole (200 mg, 0.50 mmol) and palladium on carbon (10%) (10 mg) in dioxane (10 ml), the subtitle compound was obtained.(40 mg, 86%). MS 373.2 m/z (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07138425B2 |
| Source dataset | uspto-grants-2006_11 |
| ORD ID | ord-de62845d412c4d569d189cb01c1747f2 |
| Source note | uspto-grants-2006_11 |