Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 722654Generated: October 26, 2026

2-(2-Propylamino-5-nitrophenyl)-5-(2-benzofuranyl)benzoxazole → 2-(2-Propylamino-5-aminophenyl)-5-(2-benzofuranyl)benzoxazole

https://huagongshe.com/reaction/722654

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(2-Propylamino-5-nitrophenyl)-5-(2-benzofuranyl)benzoxazoleHCID 21884328—
CatalystZincHCID 23994—
Product2-(2-Propylamino-5-aminophenyl)-5-(2-benzofuranyl)benzoxazoleHCID 21884618—

Reaction Steps

Prepared by the method of Example 47b), from 2-(2-propylamino-5-nitrophenyl)-5-(2-benzofuranyl)benzoxazole (190 mg, 0.46 mmol) and zinc (300 mg, 4.6 mmol) the subtitle compound was obtained (150 mg, 85%). The product was used directly in the next step without purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07138425B2
Source datasetuspto-grants-2006_11
ORD IDord-4448fa2a916f4fce8d80e257b7a3f86d
Source noteuspto-grants-2006_11