HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzo(B)Thiophene-2-Boronic Acid → 2-(3-Nitro-6-propylaminophenyl)-5-(2-benzothiophenyl)benzoxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzo(B)Thiophene-2-Boronic Acid | HCID 2359 | — |
| Reactant | 2-(5-bromo-1,3-benzoxazol-2-yl)-4-nitro-N-propylaniline | HCID 5303802 | — |
| Product | 2-(3-Nitro-6-propylaminophenyl)-5-(2-benzothiophenyl)benzoxazole | HCID 21884309 | — |
Reaction Steps
Prepared by the method of Example 15d), from 2-(3-nitro-6-propylaminophenyl)-5-bromobenzoxazole (400 mg, 1.59 mmol) and benzothiophene-2-boronic acid (283 mg, 1.59 mmol) the subtitle compound was obtained (386 mg, 57%). The product was used directly in the next step without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07138425B2 |
| Source dataset | uspto-grants-2006_11 |
| ORD ID | ord-b412c42a15324a1783496237910ec44d |
| Source note | uspto-grants-2006_11 |