5-Chlorovaleryl chloride → HCID 21886968, compound

HRID 722913Notes

Reaction equation

HRID 722913 reaction equation
[CH2:1]1[C:11]2=[C:12]3[C:7](=[CH:8][CH:9]=[CH:10]2)[CH2:6][CH2:5][CH2:4][N:3]3[C:2]1=[O:13].[Cl:14][CH2:15][CH2:16][CH2:17][CH2:18][C:19](Cl)=[O:20]>>[Cl:14][CH2:15][CH2:16][CH2:17][CH2:18][C:19]([C:9]1[CH:8]=[C:7]2[C:12]3=[C:11]([CH2:1][C:2](=[O:13])[N:3]3[CH2:4][CH2:5][CH2:6]2)[CH:10]=1)=[O:20]

Participants

3

Reactant 2

HCID 740895-Chlorovaleryl chlorideHCID 149184935,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinolin-2(1H)-one

Product 1

HCID 21886968HCID 21886968, compoundYield 64.9%

Procedure

Using 5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-2(1H)-one (3.46 g) and 5-chlorovaleryl chloride (3.4 g) according to the same method as that of Reference Example 1, the title compound (3.78 g) was obtained as pale yellow crystals having a melting point of 89 to 90° C.

Sources & evidence

ORD record
ord-b2ab0b844c6c46a3b1190c74e2a2907f
Source dataset
uspto-grants-2006_11
Patent number
US07138533B2

Reaction notes

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