2H-1,4-benzoxazin-3(4H)-one → HCID 21887298, compound

HRID 722917Notes

Reaction equation

HRID 722917 reaction equation
[O:1]1[C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[NH:4][C:3](=[O:11])[CH2:2]1.[Cl:12][CH2:13][CH2:14][CH2:15][CH2:16][C:17](Cl)=[O:18]>>[Cl:12][CH2:13][CH2:14][CH2:15][CH2:16][C:17]([C:9]1[CH:8]=[CH:7][C:6]2[O:1][CH2:2][C:3](=[O:11])[NH:4][C:5]=2[CH:10]=1)=[O:18]

Participants

3

Reactant 2

HCID 727572H-1,4-benzoxazin-3(4H)-oneHCID 740895-Chlorovaleryl chloride

Product 1

HCID 21887298HCID 21887298, compoundYield 66.9%

Procedure

Using 2H-1,4-benzoxazin-3(4H)-one (10.0 g) and 5-chlorovaleryl chloride (12.5 g) according to the same method as that of Reference Example 1, the title compound (12.0 g) was obtained as colorless crystals.

Sources & evidence

ORD record
ord-46dd4a03fb014b2992894f4fed4bc327
Source dataset
uspto-grants-2006_11
Patent number
US07138533B2

Reaction notes

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