Hydrochloric Acid → HCID 21873516, compound

Participants

Reaction Conditions

Reaction Steps

4-(1-Benzyl-2,2-dioxo-2,3-dihydro-1H-benzo[4,2,1]oxathiazin-5-yl)-piperazine-1-carboxylic acid tert-butyl ester was dissolved in 1 mL methanol and 1 mL of 2N ethanolic HCl was added. The solution is heated at 100° C. for 30 minutes, at which time was added approximately. 2 mL Et2O. On cooling to room temperature, 30 mg of 1-benzyl-5-piperazin-1-yl-1H-benzo[4,2,1]oxathiazine 2,2-dioxide hydrochloride precipitated as a white solid (61%). (M+H)+=360.

Provenance & Evidence