HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorobenzyl bromide → 3-[4-(4-Fluoro-benzyloxy)-phenyl]-5-(4-methyl-imidazol-1-ylmethyl)-isoxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorobenzyl bromide | HCID 68021 | — |
| Reactant | HCID 136359910 | HCID 136359910 | — |
| Product | 3-[4-(4-Fluoro-benzyloxy)-phenyl]-5-(4-methyl-imidazol-1-ylmethyl)-isoxazole | HCID 66617684 | — |
Reaction Steps
An experiment was performed in the same manner as in Example 139 to synthesize 4-[5-(4-methyl-imidazol-1-ylmethyl)-isoxazol-3-yl]-phenol as an intermediate, and then a synthesis was performed using 4-fluorobenzyl bromide in the same manner as in Example 142.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08828992B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-2e4270bcc4dd4134a7682e3898641c9e |
| Source note | uspto-grants-2014_09 |