HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 21873953, compound → HCID 21873942, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 21873953 | HCID 21873953 | — |
| Solvent | 1,1,1,3,3,3-Hexafluoro-2-propanol | HCID 13529 | — |
| Product | HCID 21873942 | HCID 21873942 | 6.4% |
Reaction Steps
1.1 g of 8-amino-7-[2,3-epoxy-1-oxo-3-(3-thienyl)propyl]-2,3-dimethylimidazo[1,2-a]pyridine are dissolved in 20 ml of hexafluoroisopropanol at room temperature, the solvent is stripped off after 19 hours and the residue is purified on silica gel (eluent: methylene chloride/methanol=100/3). 70 mg of the title compound of m.p. 222–25° C. (diethyl ether) are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07141567B2 |
| Source dataset | uspto-grants-2006_11 |
| ORD ID | ord-06ae188f6cb04c248b8462601c495ce9 |
| Source note | uspto-grants-2006_11 |