反应详情

A solution of 252C (2.6 g, 6.9 mmol) in EtOH (100 mL) was treated with ammonium formate (3.5 g, 55.3 mmol) and 10% Pd/C (390 mg). The reaction mixture was heated to reflux under a nitrogen atmosphere for three hours. The resulting suspension was filtered through a pad of celite and concentrated in vacuo to afford 1.8 g (yield: 96%) Compound 259A as a solid.

1. temperatureThe reaction mixture was heated
2. temperatureto reflux under a nitrogen atmosphere for three hours
3. filtrationThe resulting suspension was filtered through a pad of celite
4. concentrationconcentrated in vacuo