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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 723507Generated: November 1, 2026

Nitric Acid → HCID 21873584, compound

https://huagongshe.com/reaction/723507

Reaction equation

Participants

RoleNameHCIDCharge
ReactantNitric AcidHCID 944—
Reactant2-Fluoro-4-hydroxybenzonitrileHCID 2734675—
CatalystPalladiumHCID 23938—
SolventAcetic AcidHCID 176—
SolventEthanolHCID 702—
ProductHCID 21873584HCID 21873584—

Reaction Steps

This was prepared from 2-fluoro-4-hydroxy-benzonitrile by nitration (concentrated nitric acid in acetic acid at 40° C.) followed by hydrogenation in ethanol over 10% palladium/carbon.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07141564B2
Source datasetuspto-grants-2006_11
ORD IDord-f23d48f167c24968b9ca170a9adeb4a3
Source noteuspto-grants-2006_11