HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl Malonate → 7-hydroxy-2,2-dimethyl-2,3-dihydro-1H-imidazo[1,2-a]pyrimidin-5-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl Malonate | HCID 7761 | — |
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | HCID 178419513 | HCID 178419513 | — |
| Product | 7-hydroxy-2,2-dimethyl-2,3-dihydro-1H-imidazo[1,2-a]pyrimidin-5-one | HCID 136269314 | — |
Reaction Steps
The process is carried out according to the procedure described in stage g of Example 1, using 5 g of 4,4-dimethylimidazolidin-2-ylideneamine hydrobromide, 4 ml of diethyl malonate and 2.8 g of sodium methoxide. 4.5 g of 7-hydroxy-2,2-dimethyl-2,3-dihydro-1H-imidazo[1,2-a]pyrimidin-5-one are thus obtained in the form of a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08828997B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-2c312285eb3c4331af3247db26bef229 |
| Source note | uspto-grants-2014_09 |