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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 724143Generated: October 25, 2026

2-Chloro-4,6-dimethyl-3-nitropyridine → (2S)-1-{4-[(4,6-dimethyl-3-nitro-2-pyridinyl)amino]phenyl}-2-propanol

https://huagongshe.com/reaction/724143

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-4,6-dimethyl-3-nitropyridineHCID 21875578—
Reactant(S)-1-(4-aminophenyl)propan-2-olHCID 67099494—
Product(2S)-1-{4-[(4,6-dimethyl-3-nitro-2-pyridinyl)amino]phenyl}-2-propanolHCID 67099429—

Reaction Steps

The title compound was prepared according to the procedure described in step 1 of Example 162 from 2-chloro-4,6-dimethyl-3-nitropyridine (step 2 of Example 1) and (2S)-1-(4-aminophenyl)-2-propanol (step 2 of Example 248).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07141580B2
Source datasetuspto-grants-2006_11
ORD IDord-46fb849066174de5bbbbdb966bc22ade
Source noteuspto-grants-2006_11