HuagongsheHuagongshe Chemistry Print Report · For research reference only
5,6-Dihydropyrrolo[1,2-c]imidazol-7-one → 7-(5-fluorobenzo[b]thiophen-2-yl)-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5,6-Dihydropyrrolo[1,2-c]imidazol-7-one | HCID 11170960 | — |
| Reactant | 5-Fluoro-1-benzothiophene | HCID 11815950 | — |
| Product | 7-(5-fluorobenzo[b]thiophen-2-yl)-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-ol | HCID 9943445 | 34.6% |
Reaction Steps
The reaction and purification in the same manner as in Example 1 using 5-fluorobenzo[b]thiophene (0.30 g) and 5,6-dihydro-7H-pyrrolo[1,2-c]imidazol-7-one (0.18 g) afforded the title compound (0.14 g) as colorless crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07141598B2 |
| Source dataset | uspto-grants-2006_11 |
| ORD ID | ord-3b686b7144a84f608b988a51352b9256 |
| Source note | uspto-grants-2006_11 |