HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4-Methoxyphenyl)boronic acid → 4-(4'-Methoxy-biphenyl-3-yl)-5-methyl-2-(4-trifluoromethyl-phenyl)-oxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4-Methoxyphenyl)boronic acid | HCID 201262 | — |
| Reactant | 2-[4-(Trifluoromethyl)phenyl]-4-(4-bromophenyl)-5-methyloxazole | HCID 10691278 | — |
| Product | 4-(4'-Methoxy-biphenyl-3-yl)-5-methyl-2-(4-trifluoromethyl-phenyl)-oxazole | HCID 9931322 | — |
Reaction Steps
The title compound was prepared from 4-(4-bromo-phenyl)-5-methyl-2-(4-trifluoromethyl-phenyl)-oxazole, and 4-methoxy-benzeneboronic acid in substantially the same manner, as described in Example 1 step c, and was obtained as a white solid, mp 93–94° C.; MS m/e 409 (M+);
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07141672B2 |
| Source dataset | uspto-grants-2006_11 |
| ORD ID | ord-7b5eddcb2155406c8525ff68f1bcbcab |
| Source note | uspto-grants-2006_11 |