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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 724453Generated: November 4, 2026

Methyl bromoacetate → {3,5-Dibromo-4'-[5-methyl-2-(4-trifluoromethyl-phenyl)-oxazol-4-yl]-biphenyl-4-yloxy}-acetic acid

https://huagongshe.com/reaction/724453

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl bromoacetateHCID 60984—
ReactantHCID 9915604HCID 9915604—
Product{3,5-Dibromo-4'-[5-methyl-2-(4-trifluoromethyl-phenyl)-oxazol-4-yl]-biphenyl-4-yloxy}-acetic acidHCID 10348783—

Reaction Steps

The title compound was prepared from 3,5-dibromo-4′-[5-methyl-2-(4-trifluoromethyl-phenyl)-oxazol-4-yl]-biphenyl-4-ol, and methyl bromoacetate in substantially the same manner, as described in Example 5, and was obtained as an off-white solid, mp 165–166° C.; MS m/e 609 (M+);

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07141672B2
Source datasetuspto-grants-2006_11
ORD IDord-a8e5e9164fb948ffa719b59eca55cbac
Source noteuspto-grants-2006_11