Potassium Carbonate → HCID 86596725, compound

HRID 724494Notes

Reaction equation

HRID 724494 reaction equation
[C:1](=O)([O-])[O-].[K+].[K+].[CH3:7][CH2:8][O:9][C:10]([CH2:12]P(OCC)(OCC)=O)=[O:11].[CH3:21][CH:22]([CH3:26])[CH2:23][CH:24]=O>O>[CH2:8]([O:9][C:10]([CH2:12]/[CH:1]=[CH:24]/[CH2:23][CH:22]([CH3:26])[CH3:21])=[O:11])[CH3:7]

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 115523-MethylbutanalHCID 13345Triethyl phosphonoacetate

Product 1

HCID 86596725HCID 86596725, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Conditions

Temperature
25 °C

Procedure

1 mol (138 g) of potassium carbonate was dissolved in 100 ml of water and cooled in ice water. 0.6 mol (120 ml) of phosphonoacetic acid triethyl ester and 0.5 mol (43.1 g) of 3-methylbutanal were added and the mixture was stirred for 20 hours with the temperature slowly being raised to 25° C. The reaction batch was then diluted with 150 ml of water and extracted four times with diethyl ether. The organic phase was dried with magnesium sulfate and evaporated in a rotary evaporator. A clear liquid was obtained. The crude yield amounted to 75.8 g (97% of theoretical).

Workup

  1. extractionextracted four times with diethyl ether
  2. dry with materialThe organic phase was dried with magnesium sulfate
  3. customevaporated in a rotary evaporator
  4. customA clear liquid was obtained
  5. customThe crude yield

Sources & evidence

ORD record
ord-0d43d6d495014d10952bb51122424dbf
Source dataset
uspto-grants-2006_11
Patent number
US07141695B2

Reaction notes

Loading…