HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lawesson's reagent → {2-[(6-Nitro-1h-indole-2-carbothioyl)amino]ethyl}carbamic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lawesson's reagent | HCID 87949 | — |
| Reactant | {2-[(6-Nitro-1H-indole-2-carbonyl)-amino]-ethyl}-carbamic acid tert-butyl ester | HCID 58747124 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | {2-[(6-Nitro-1h-indole-2-carbothioyl)amino]ethyl}carbamic acid tert-butyl ester | HCID 58747101 | — |
Reaction Steps
To a suspension of 35 in toluene is added Lawesson's Reagent. The suspension is heated at reflux while stirring for 1 h. The reaction mixture is cooled over ice to precipitate the product. The product is then filtered, washed with hexane, and dried to give 156.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07141680B2 |
| Source dataset | uspto-grants-2006_11 |
| ORD ID | ord-2b268c0acd094ae48269859216e28684 |
| Source note | uspto-grants-2006_11 |