反应详情

A solution of 1.37-C of Step 3 (87 mg, 0.16 mmol) in methylene chloride (5 mL) and ethanol (0.2 mL) was treated with HCl gas for 1 h. Additional methylene chloride was added during the reaction to replenish the amount which was evaporated during the bubbling of HCl. The reaction mixture was concentrated and used immediately in the next reaction.

1. customwas evaporated during the
2. custombubbling of HCl
3. concentrationThe reaction mixture was concentrated
4. customused immediately in the next reaction