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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 724623Generated: November 3, 2026

1-Bromo-4-(methylsulphonyl)benzene → [4'-(Methylsulfonyl)[1,1'-biphenyl]-4-yl]methanol

https://huagongshe.com/reaction/724623

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Bromo-4-(methylsulphonyl)benzeneHCID 77014—
Reactant(3'-Methanesulfonyl-biphenyl-4-yl)-methanolHCID 21879230—
Product[4'-(Methylsulfonyl)[1,1'-biphenyl]-4-yl]methanolHCID 21878562—

Reaction Steps

This compound was prepared in a manner analogous to the preparation of (3′-methanesulfonyl-biphenyl-4-yl)-methanol (WO 01/70753, Example 27) using 1-bromo-4-methanesulfonyl-benzene as the starting material. LCMS found for C14H15O3S (M+H)+: m/z=263.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07141596B2
Source datasetuspto-grants-2006_11
ORD IDord-db3460dc0bf44c5492b0ac05b019275a
Source noteuspto-grants-2006_11