Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 3-Chloro-2-(chloromethyl)-2-methylpropionic acid | HCID 105411 | — |
| Catalyst | Dimethylformamide | HCID 6228 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 4301-04-6 | HCID 4321027 | — |
Reaction Steps
DMF (1 drop) was added to a solution of 2,2-bis(chloromethyl)propanoic acid (1.4 g) in DCM (1.5 ml), the solution was cooled to 0° C. and oxalyl chloride (0.75 ml) added. After gas evolution had stopped the mixture was concentrated in vacuo to give the sub-title compound as a yellow oil (1.51 g) which was used directly in the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05705456 |
|---|
| Source dataset | uspto-grants-1998_01 |
|---|
| ORD ID | ord-51088c7e1b4740c4b2634ad1b954d56c |
|---|
| Source note | uspto-grants-1998_01 |
|---|
