4-Bromo-2-methylpyridine → HCID 19711129, compound

Participants

Reaction Steps

By a procedure analogous to that described in Example 51b, 48 mg (0.15 mmol) of 2-chloro-5,11-dihydro-11-ethyl-8-ethynyl-5-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one coupled with 4-bromo-2-picoline (31 mg, 0.15 mmol) to provide 51 mg (83%) of the title compound.

Provenance & Evidence