HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 4-(1-aminocyclopropyl)benzoate hydrochloride → HCID 67958579, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 4-(1-aminocyclopropyl)benzoate hydrochloride | HCID 66824369 | — |
| Reactant | 2-(3-(2,4-Difluorophenoxy)azetidin-1-yl)-5-(trifluoromethyl)nicotinic acid | HCID 67958434 | — |
| Product | HCID 67958579 | HCID 67958579 | 76.5% |
Reaction Steps
The title compound (D178) (106 mg) was prepared according to the experimental procedure described in Description 144 starting from 2-(3-(2,4-difluorophenoxy)azetidin-1-yl)-5-(trifluoromethyl)nicotinic acid (D127) (95 mg, 0.253 mmol) and methyl 4-(1-aminocyclopropyl)benzoate (D7) (57.79 mg, 0.253 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08828987B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-49b916ba6c0140f5a2f13ab29a848085 |
| Source note | uspto-grants-2014_09 |