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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 72522Generated: October 27, 2026

Methyl 4-(1-aminocyclopropyl)benzoate hydrochloride → HCID 67958218, compound

https://huagongshe.com/reaction/72522

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 4-(1-aminocyclopropyl)benzoate hydrochlorideHCID 66824369—
Reactant2-(3-((5-Methylisoxazol-3-yl)oxy)azetidin-1-yl)-5-(trifluoromethyl)nicotinic acidHCID 67958635—
ProductHCID 67958218HCID 6795821870.4%

Reaction Steps

The title compound (D180) (20 mg) was prepared according to the experimental procedure described in Description 144 starting from 2-(3-((5-methylisoxazol-3-yl)oxy)azetidin-1-yl)-5-(trifluoromethyl)nicotinic acid (D129) (19 mg, 0.055 mmol) and methyl 4-(1-aminocyclopropyl)benzoate hydrochloride (D7) (12.6 mg, 0.055 mmol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08828987B2
Source datasetuspto-grants-2014_09
ORD IDord-e80b043fa4534593be42bae7a2e9b04c
Source noteuspto-grants-2014_09