Acrylamide → Diphenylmethane

HRID 725281Notes

Reaction equation

HRID 725281 reaction equation
[CH:1](O)([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C(N)(=O)C=C>C(Cl)Cl>[C:2]1([CH2:1][C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=2)[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 6579AcrylamideHCID 7037Benzhydrol

Product 1

HCID 7580Diphenylmethane

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

To a solution of benzhydrol (184 mg, 1 mmol) in methylene chloride (1 mL) is added 0.2 g 85 weight percent HF/15 weight percent acrylamide polymer, 175,000 m. wt., and the solution stirred until complete by TLC. The liquid is decanted and the gel washed with 2×1 mL methylene chloride. The organic layers are combined and washed with 1 mL water, 1 mL NaHCO3, dried through MgSO4 and evaporated. Diphenylmethane is afforded.

Workup

  1. customThe liquid is decanted
  2. washthe gel washed with 2×1 mL methylene chloride
  3. washwashed with 1 mL water, 1 mL NaHCO3
  4. dry with materialdried through MgSO4
  5. customevaporated

Sources & evidence

ORD record
ord-7b33ca78013643bcad282c373b4ce63d
Source dataset
uspto-grants-1998_01
Patent number
US05705717

Reaction notes

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