反应详情

A suspension of 2.6 g of (3,4-dihydroxy-5-nitrobenzoyl)methyl acetate in 20 ml of ethanol and 20 ml of 1N hydrochloric acid is heated to boiling under reflux for 5 hours. The reaction mixture is then evaporated, the residue is distilled with distilled with toluene and then recrystallized from ethanol. There is obtained 2,3',4'-trihydroxy-5'-nitroacetophenone of m.p. 208°-210°.

1. temperatureis heated
2. temperatureunder reflux for 5 hours
3. customThe reaction mixture is then evaporated
4. distillationthe residue is distilled
5. distillationwith distilled with toluene
6. customrecrystallized from ethanol