1-Amino-3,3-diethoxypropane → HCID 19708586, compound

HRID 725765Notes

Reaction equation

HRID 725765 reaction equation
[Cl:1][C:2]1[C:3](OS(O)(=O)=O)=[C:4]2[C:9](=[C:10]([C:12]([F:15])([F:14])[F:13])[CH:11]=1)[NH:8][C:7](=[O:16])[C:6]([C:17](=[O:21])[CH:18]([CH3:20])[CH3:19])=[C:5]2C.[CH2:28]([O:30][CH:31]([O:35][CH2:36][CH3:37])[CH2:32][CH2:33][NH2:34])[CH3:29]>>[Cl:1][C:2]1[CH:3]=[C:4]2[C:9](=[C:10]([C:12]([F:15])([F:13])[F:14])[CH:11]=1)[NH:8][C:7](=[O:16])[C:6]([C:17](=[O:21])[CH:18]([CH3:19])[CH3:20])=[C:5]2[NH:34][CH2:33][CH2:32][CH:31]([O:35][CH2:36][CH3:37])[O:30][CH2:28][CH3:29]

Participants

3

Reactant 2

HCID 5210291-Amino-3,3-diethoxypropaneHCID 86751877HCID 86751877, compound

Product 1

HCID 19708586HCID 19708586, compoundYield 78%

Procedure

6-Chloro-3-isobutyryl-4-methylsulfoxy-8-trifluoromethyl-2-quinolinone (379 mg, 1 mmol) and 3,3-diethoxypropylamine (147 mg, 1 mmol) were used and the reaction was carried out as in the above process of example 1 to obtain the desired product (335 mg, yield: 78%).

Sources & evidence

ORD record
ord-cd2cf137b3f1482fa1cd2ec78309dd9d
Source dataset
uspto-grants-1998_01
Patent number
US05707931

Reaction notes

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