HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Azabicyclo[3.2.2]nonane → 3-(4-Methoxy-1-naphthylsulfonyl)-3-azabicyclo[3.2.2]nonane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Azabicyclo[3.2.2]nonane | HCID 9240 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 4-Methoxynaphthalene-1-sulfonyl chloride | HCID 16775501 | — |
| Product | 3-(4-Methoxy-1-naphthylsulfonyl)-3-azabicyclo[3.2.2]nonane | HCID 19708712 | — |
Reaction Steps
The title compound was prepared by reacting 4-methoxy-1-naphthalenesulfonyl chloride (0.25 g) with 3-azabicyclo[3.2.2]nonane (0.12 g) in the presence of DIEA (0.16 g) using a procedure similar to that used in Example 5. Yield: 0.24 g, mp 167.7°-169.5° C. (soften 166.1° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05707985 |
| Source dataset | uspto-grants-1998_01 |
| ORD ID | ord-31bc1180cd57475cb31c7564cb470924 |
| Source note | uspto-grants-1998_01 |