HCID 19608428, compound → HCID 178422871, compound

Participants

Reaction Conditions

Reaction Steps

A toluene solution (2 ml) containing 0.90 g of 3-aminopyrazole and 1.90 g of methyl 2-methyl-β-oxo-1,3-dioxolane-2-valerate was refluxed with heating at 115° C. for 1 hour, allowed to cool and then concentrated under reduced pressure. Diethyl ether was added to the residue. The crystals precipitated were collected and washed with diethyl ether to provide 1.85 g of 7-hydroxy-5-[2-(2-methyl-l,3-dioxolane-2-yl)ethyl]pyrazolo[1,5-a]pyrimidine as colorless crystals.

Provenance & Evidence