Methanol → HCID 178501119, compound

Participants

Reaction Steps

103 g of trans-4-aminomethyl-cyclohexanecarboxylic acid are dissolved in 1 l of methanol and 48 ml of thionylchloride are added dropwise thereto whilst cooling with ice. After 2 hours at ambient temperature the solvent is distilled off using a rotary evaporator, the residue is stirred with 300 ml of tert.-butylmethylether, suction filtered and dried.

Provenance & Evidence