Methylamine → HCID 178485737, compound

HRID 725840Notes

Reaction equation

HRID 725840 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([NH:8][C:9]2[C:10]3[N:18]=[C:17]([NH:19][C@H:20]4[CH2:25][CH2:24][C@H:23]([C:26](O)=[O:27])[CH2:22][CH2:21]4)[N:16]=[CH:15][C:11]=3[N:12]=[CH:13][N:14]=2)[CH:5]=[CH:6][CH:7]=1.S(Cl)(Cl)=O.[CH3:33][NH2:34]>>[CH3:1][C:2]1[CH:3]=[C:4]([NH:8][C:9]2[C:10]3[N:18]=[C:17]([NH:19][C@H:20]4[CH2:25][CH2:24][C@H:23]([C:26]([NH:34][CH3:33])=[O:27])[CH2:22][CH2:21]4)[N:16]=[CH:15][C:11]=3[N:12]=[CH:13][N:14]=2)[CH:5]=[CH:6][CH:7]=1

Participants

4

Procedure

Prepared from compound 134 of Example 1 by reaction with thionyl chloride and methylamine.

Sources & evidence

ORD record
ord-e5aa006293114babb2e04606c75733c6
Source dataset
uspto-grants-1998_01
Patent number
US05707989

Reaction notes

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