Isopropyl isocyanate → HCID 22611570, compound

HRID 725990Notes

Reaction equation

HRID 725990 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][CH:6]=[C:5]2[CH:11]1[CH2:16][CH2:15][N:14]([CH3:17])[CH2:13][CH2:12]1.[CH:18]([N:21]=[C:22]=[O:23])([CH3:20])[CH3:19]>>[CH:18]([NH:21][C:22]([NH:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][CH:6]=[C:5]2[CH:11]1[CH2:16][CH2:15][N:14]([CH3:17])[CH2:13][CH2:12]1)=[O:23])([CH3:20])[CH3:19]

Participants

3

Reactant 2

HCID 61277Isopropyl isocyanateHCID 118312203-(1-Methylpiperidin-4-yl)-1h-indol-5-amine

Product 1

HCID 22611570HCID 22611570, compound

Procedure

Beginning with 15.0 mg 0.0655 mMol) 5-amino-3-(1-methyl-piperidin-4-yl)-1H-indole and 11.13 mg (0.131 mMol) isopropyl isocyanate, 21.9 mg of the title compound were recovered.

Sources & evidence

ORD record
ord-8e715ba04138478e8b305c6d215bd92f
Source dataset
uspto-grants-1998_01
Patent number
US05708008

Reaction notes

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