Hydrochloric Acid → 4-Amidinobenzoic acid hydrochloride

HRID 726426Notes

Reaction equation

HRID 726426 reaction equation
[C:1]([C:4]1[CH:12]=[CH:11][C:7]([C:8](N)=[O:9])=[CH:6][CH:5]=1)(=[NH:3])[NH2:2].[ClH:13].[OH2:14]>>[ClH:13].[C:1]([C:4]1[CH:12]=[CH:11][C:7]([C:8]([OH:14])=[O:9])=[CH:6][CH:5]=1)(=[NH:3])[NH2:2]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 962WaterHCID 5960194-Amidinobenzamide

Product 1

HCID 448908304-Amidinobenzoic acid hydrochloride

Procedure

4-Amidinobenzamide (commercially available one, 7.8 g) is dissolved in water (200 ml), and thereto is added conc. hydrochloric acid (200 ml), and the mixture is stirred at a temperature below 100° C. for 9 hours. The mixture is cooled, and the precipitated crystals are collected by filtration.

Workup

  1. temperatureThe mixture is cooled
  2. filtrationthe precipitated crystals are collected by filtration

Sources & evidence

ORD record
ord-9926f76b75794862b41329a107dc3485
Source dataset
uspto-grants-1998_01
Patent number
US05707994

Reaction notes

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