Hydrochloric Acid → HCID 86751950, compound

Participants

Reaction Steps

The compound (100 mg) obtained in the above (5) is dissolved in dichloromethane (2 ml), and thereto are added succinic anhydride (53 mg) and triethylamine (73 μl), and the mixture is stirred at room temperature for 45 minutes. To the mixture is added 1N hydrochloric acid, and the mixture is extracted three time with ethyl acetate. The extract is washed twice with a saturated brine, and the organic layer is dried over anhydrous magnesium sulfate. The desiccant is removed by filtration, and the filtrate is concentrated under reduced pressure to give the title compound (139 mg).

Provenance & Evidence