Cyclopropylamine → HCID 11786689, compound

Participants

Reaction Steps

Using 0.5 g of (Z)-[1-[4-[2-(2-ethyl-1H-imidazol-1-yl)benzoylamino]benzoyl]-4,4-difluoro-2,3,4,5-tetrahydro-1H-1-benzazepin-5-ylidene]acetic acid and 0.074 ml of cylopropylamine, a similar procedure as in Example 11 was repeated to obtain 325 mg of (Z)-4'-[[5-[(N-cyclopropylcarbamoyl)methylene]-4,4-difluoro-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]carbonyl]-2-(2-ethyl-1H-imidazol-1-yl) benzanilide.

Provenance & Evidence