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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 727073Generated: October 31, 2026

Sodium Cyanide → 2,4-Diamino-5-(2,4-dichlorophenyl)-6-cyanomethyl-pyrimidine

https://huagongshe.com/reaction/727073

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium CyanideHCID 8929—
ReactantHCID 19705067HCID 19705067—
SolventDimethylformamideHCID 6228—
Product2,4-Diamino-5-(2,4-dichlorophenyl)-6-cyanomethyl-pyrimidineHCID 19705111—

Reaction Steps

This compound was prepared from 2,4-diamino-5-(2,4-dichlorophenyl)-6-bromomethyl-pyrimidine (Example 53) by reaction with sodium cyanide in DMF at room temperature, mp. 249°-251° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05712276
Source datasetuspto-grants-1998_01
ORD IDord-e0c17b21b5fb4852b7c8579b45053480
Source noteuspto-grants-1998_01