Triphenylphosphine → (2,3-Dihydro-2,2-dimethylbenzofuran-7-ylmethyl)triphenylphosphonium bromide

HRID 727168Notes

Reaction equation

HRID 727168 reaction equation
[CH3:1][C:2]1([CH3:13])[CH2:6][C:5]2[CH:7]=[CH:8][CH:9]=[C:10]([CH2:11][Br:12])[C:4]=2[O:3]1.[C:14]1([P:20]([C:27]2[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=2)[C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>C1(C)C=CC=CC=1>[Br-:12].[CH3:1][C:2]1([CH3:13])[CH2:6][C:5]2[CH:7]=[CH:8][CH:9]=[C:10]([CH2:11][P+:20]([C:21]3[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=3)([C:27]3[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=3)[C:14]3[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=3)[C:4]=2[O:3]1

Participants

4

Reactant 2

HCID 11776TriphenylphosphineHCID 42719367-(bromomethyl)-2,2-dimethyl-3H-1-benzofuran

Product 1

HCID 19705240(2,3-Dihydro-2,2-dimethylbenzofuran-7-ylmethyl)triphenylphosphonium bromide

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

This compound is prepared in a manner analogous to that of Step A of Example 2, using 11.8 grams (0.049 mole) of 2,3-dihydro-2,2-dimethylbenzofuran-7-ylmethyl bromide and 13.0 grams (0.050 mole) of triphenylphosphine in about 100 mL of toluene, yielding (2,3-dihydro-2,2-dimethylbenzofuran-7-ylmethyl)triphenylphosphonium bromide.

Workup

  1. customThis compound is prepared in a manner analogous to that of Step A of Example 2

Sources & evidence

ORD record
ord-471479e83d6b42a3a09ffad549adc9df
Source dataset
uspto-grants-1998_01
Patent number
US05712281

Reaction notes

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