HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(2,2,3,3-Tetrafluoro-2,3-dihydrobenzofuran-7-ylmethyl)cyclohexanone → 2,4-Diamino-6-(2,2,3,3-tetrafluoro-2,3-dihydrobenzofuran-7-ylmethyl)-5,6,7,8-tetrahydroquinazoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(2,2,3,3-Tetrafluoro-2,3-dihydrobenzofuran-7-ylmethyl)cyclohexanone | HCID 19705266 | — |
| Reactant | HCID 178418324 | HCID 178418324 | — |
| Solvent | Diethylene Glycol Monoethyl Ether | HCID 8146 | — |
| Product | 2,4-Diamino-6-(2,2,3,3-tetrafluoro-2,3-dihydrobenzofuran-7-ylmethyl)-5,6,7,8-tetrahydroquinazoline | HCID 19705208 | — |
Reaction Steps
This compound is prepared in a manner analogous to that of Example 1, using 3.9 grams (0.013 mole) of 4-(2,2,3,3-tetrafluoro-2,3-dihydrobenzofuran-7-ylmethyl)cyclohexanone and 1.2 grams (0.014 mole) of cyanoguanidine in 2-(2-ethoxyethoxy)ethanol, yielding 2,4-diamino-6-(2,2,3,3-tetrafluoro-2,3-dihydrobenzofuran-7-ylmethyl)-5,6,7,8-tetrahydroquinazoline.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05712281 |
| Source dataset | uspto-grants-1998_01 |
| ORD ID | ord-38f53b407f404454a5a1ef0c2d4c2514 |
| Source note | uspto-grants-1998_01 |