HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 19705202, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 1-(Bromomethyl)-3-(trifluoromethyl)benzene | HCID 123061 | — |
| Reactant | 1,4-Dioxaspiro(4.5)decan-8-ol | HCID 567352 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 19705202 | HCID 19705202 | — |
Reaction Steps
This compound is prepared in a manner analogous to that of Step D of Example 9, using 4.7 grams (0.030 mole) of 1,4-dioxaspiro[4.5]decan-8-ol (prepared as in Step B of Example 8), 7.2 grams (0.030 mole) of 3-trifluoromethylphenylmethyl bromide, and 1.3 grams (0.033 mole) of sodium hydride (60% in mineral oil) in 60 mL of toluene, yielding 8-(3-trifluoromethyl phenyl methoxy)-1,4-dioxaspiro[4.5]decane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05712281 |
| Source dataset | uspto-grants-1998_01 |
| ORD ID | ord-d98ef5b0948f487b8cffad229168a104 |
| Source note | uspto-grants-1998_01 |