HCID 22101804, compound → HCID 54365815, compound

HRID 727257Notes

Reaction equation

HRID 727257 reaction equation
[N:1]([CH:4]([C:11]1[CH:15]=[CH:14][O:13][CH:12]=1)[C:5]1[S:9][CH:8]=[N:7][C:6]=1[CH3:10])=[N+]=[N-]>C(O)C.[Pd]>[O:13]1[CH:14]=[CH:15][C:11]([CH:4]([NH2:1])[C:5]2[S:9][CH:8]=[N:7][C:6]=2[CH3:10])=[CH:12]1

Participants

4

Reactant 1

HCID 22101804HCID 22101804, compound

Product 1

HCID 54365815HCID 54365815, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

The product from Example 53 in ethanol was shaken with 10% palladium-on-charcoal under an atmosphere of hydrogen for 3 hours. The catalyst was filtered off and the filtrate was evaporated to dryness. Flash chromatography of the residue thus obtained gave the title compound.

Workup

  1. filtrationThe catalyst was filtered off
  2. customthe filtrate was evaporated to dryness
  3. customFlash chromatography of the residue thus obtained

Sources & evidence

ORD record
ord-12379d04d2b743b880744b36cb02ec56
Source dataset
uspto-grants-1998_01
Patent number
US05712299

Reaction notes

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