Hydrochloric Acid → HCID 10656224, compound

Participants

Reaction Conditions

Reaction Steps

N-(4-Methoxy-2,3-dihydro-1H-phenalen-2-yl)acetamide (5.95mmol; 1.52g) is dissolved in 20 cm3 of ethanol to which are added 54 cm3 of 10% HCl. The mixture is maintained at 90° C. for 20 h. After cooling, 10% NaOH solution is added until the pH is basic and the amine is extracted with CH2Cl2. The organic phase is dried over MgSO4 and evaporated under reduced pressure. The title amine is thus isolated without further purification.

Provenance & Evidence