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0 °C

A mixture of 36 g (95.3 mmol) of 2-amino-5-bromo-3-iodobenzenesulphonic acid and 12.2 g (95.3 mmol) of 2-thienylboronic acid in 140 ml of 1,2-dimethoxyethane in the presence of 5.5 g of tetrakis(triphenylphosphine)palladium (0) and 30.3 g of sodium carbonate is heated at 70°-75° C. for 8.5 hours. The solvent is evaporated off under vacuum, the mixture is cooled to 0° C. and washed with water to pH=7, and the residue is then taken up in an ether/ethanol mixture (95:5).

1. temperatureis heated at 70°-75° C. for 8.5 hours
2. customThe solvent is evaporated off under vacuum
3. washwashed with water to pH=7