Hydrogen Bromide → HCID 19706190, compound

HRID 727486Notes

Reaction equation

HRID 727486 reaction equation
OCC(CO)([C:9]([O:11]CC)=[O:10])C(OCC)=O.Br.[C:17]([S:21][C:22]([CH3:25])([CH3:24])[CH3:23])([CH3:20])(C)C.[K]>>[CH3:23][C:22]([CH:25]([C:22]([S:21][CH2:17][CH3:20])([CH3:24])[CH3:23])[C:9]([OH:11])=[O:10])([S:21][CH2:17][CH3:20])[CH3:24]

Participants

4

Reactant 3

HCID 260Hydrogen BromideHCID 311844Propanedioic acid, 2,2-bis(hydroxymethyl)-, 1,3-diethyl esterHCID 86751985HCID 86751985, compound

Product 1

HCID 19706190HCID 19706190, compound

Procedure

Synthesis analogous to Example 13. The bis-(1,1-dimethyl-ethylthiomethyl)-acetic acid was synthesized from diethyl bis-(hydroxymethyl)-malonate by reaction with hydrogen bromide and subsequent replacement of the resulting β,β'-dibromoisobutyric acid with potassium tert.-butylsulfide.

Workup

  1. customSynthesis analogous to Example 13

Sources & evidence

ORD record
ord-a765ec7e9d3c4b48acea506ce7602733
Source dataset
uspto-grants-1998_01
Patent number
US05712417

Reaction notes

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