HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenol → 2,2,2-Trifluoro-1-(4-hydroxyphenyl)ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenol | HCID 996 | — |
| Reactant | Trifluoroacetyl chloride | HCID 61106 | — |
| Product | 2,2,2-Trifluoro-1-(4-hydroxyphenyl)ethanone | HCID 11446818 | — |
Reaction Steps
0.1 mol of phenol and 0.1 mol of trifluoroacetyl chloride are reacted analogously to Example 4 to give 4-trifluoroacetylphenol. The latter is esterified using carboxylic acids and DCC. With p-pentylbenzoic acid, 4-trifluoroacetylphenyl pentylbenzoate, mp. 27° C., Δε=26.7, is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05045229 |
| Source dataset | uspto-grants-1991_09 |
| ORD ID | ord-7c874369ad0347f4bf10c54a22bc98c0 |
| Source note | uspto-grants-1991_09 |