HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-[4-[1-(1-Imidazolyl)-butyl]-phenyl]-ethanol → 4'-[1-(1-Imidazolyl)-butyl]-acetophenone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-[4-[1-(1-Imidazolyl)-butyl]-phenyl]-ethanol | HCID 19825177 | — |
| Catalyst | HCID 178418406 | HCID 178418406 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 4'-[1-(1-Imidazolyl)-butyl]-acetophenone | HCID 19825154 | 50.4% |
Reaction Steps
200 mg of the alcohol of example 7 is stirred in 10 ml of methylene chloride with 1 g of manganese dioxide overnight. It is suctioned off, concentrated by evaporation and the residue is distilled at 180° C./0.03 hPa. 100 mg of the title compound is obtained as colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05045558 |
| Source dataset | uspto-grants-1991_09 |
| ORD ID | ord-68934ef1a08b4ddeaccceb3e340fedc0 |
| Source note | uspto-grants-1991_09 |