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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 727851Generated: November 3, 2026

Tetrahydrofuran → 4-[1-(1-Imidazolyl)-butyl]-benzophenone

https://huagongshe.com/reaction/727851

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
Reactant4-[1-(1-Imidazolyl)-butyl]-benzonitrileHCID 14514362—
ReactantHCID 178418255HCID 178418255—
Product4-[1-(1-Imidazolyl)-butyl]-benzophenoneHCID 14514365—

Reaction Steps

The 4-[1-(1-imidazolyl)-butyl]-benzonitrile is reacted with phenylmagnesium bromide under standard conditions analogously to example 11 in tetrahydrofuran. 0.83 g of 4-[1-(1-imidazolyl)-butyl]-benzophenone with a boiling point of 175° C./0.03 mbar is obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05045558
Source datasetuspto-grants-1991_09
ORD IDord-a59209496495444088583fc45593208a
Source noteuspto-grants-1991_09