HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 4-[1-(1-Imidazolyl)-butyl]-benzoic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Methanol | HCID 887 | — |
| Reactant | 4-[1-(1-Imidazolyl)-butyl]-benzoic acid, hydrochloride | HCID 14514369 | — |
| Product | 4-[1-(1-Imidazolyl)-butyl]-benzoic acid methyl ester | HCID 14514374 | — |
Reaction Steps
1.0 of 4-[1-(1-imidazolyl)-butyl]-benzoic acid, hydrochloride (of example 2) is dissolved in 30 ml of methanol, hydrochloric-acid gas is introduced for 10 minutes, refluxed for 30 minutes and concentrated by evaporation. The residue is distilled on a bulb tube, boiling point 190° C./0.03 mbar. 0.55 g of 4-[1-(1-imidazolyl)-butyl]-benzoic acid methyl ester is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05045558 |
| Source dataset | uspto-grants-1991_09 |
| ORD ID | ord-35e1812d34b64fc0ac158ac903270011 |
| Source note | uspto-grants-1991_09 |