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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 727856Generated: November 1, 2026

HCID 54144148, compound → HCID 14514373, compound

https://huagongshe.com/reaction/727856

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 54144148HCID 54144148—
ReactantHCID 178418361HCID 178418361—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 14514373HCID 1451437396.5%

Reaction Steps

1.08 g of 3-[1-(1-imidazolyl)-butyl]-cinnamic acid (example 42) is dissolved in 20 ml of methanol and mixed with 100 mg of palladium on carbon (10%) and hydrogenated at normal pressure. After 2 hours, the reaction mixture does not take up any more hydrogen. Then the catalyst is filtered off on kieselguhr and the filtrate is concentrated by evaporation in a vacuum. 1.05 g of 3-[3-[1-(1-imidazolyl)-butyl]-phenyl]propionic acid is obtained

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05045558
Source datasetuspto-grants-1991_09
ORD IDord-6abc96a3bef9496a8fb12a8eb5475320
Source noteuspto-grants-1991_09