反应详情

43 g (0.15 mole) of 4-(2-acetoxyethoxy)-benzophenone are dissolved in 60 ml of ethanol and boiled with 17 ml of 32% strength sodium hydroxide solution under reflux, with stirring, for 20 minutes. After cooling, the reaction mixture is neutralized with hydrochloric acid, whereupon the end product is precipitated as a white solid. The reaction mixture is poured into 500 ml of water, and the solid is filtered off with suction, washed and dried in vacuo at 50° C. for 5 hours. This gives 35 g (95%) of 4-(2-hydroxyethoxy)-benzophenone, melting point 82° C.

1. temperatureunder reflux
2. temperatureAfter cooling
3. customis precipitated as a white solid
4. additionThe reaction mixture is poured into 500 ml of water
5. filtrationthe solid is filtered off with suction
6. washwashed
7. customdried in vacuo at 50° C. for 5 hours